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1. Which of the following statements is true of the psychiatric use…
1. Which of the following statements is true of the psychiatric use of LSD and psilocybin in the 1950s and 1960s in the United States?
a) LSD and psilocybin were used as tranquilizers in the 1950s and 1960s on psychiatric patients to reduce their awareness of conflicts and problems.
b) The use of LSD and psilocybin to treat psychological disorders was criminalized by the U.S. Supreme Court in the mid-1950s.
c) LSD and psilocybin were marketed in the 1950s as a way to help psychiatric patients resolve their problems and access repressed memories.
2. Identify a true statement about the prevalence of hallucinogen use in the United States.
a) The popularity of psilocybin peaked in the 1990s and 2000s and then began to decrease due to reduced availability.
b) MDMA use increased in the early part of the twenty-first century, but it is now on the decline.
c) The illegal use of PCP peaked in 1979, and its popularity has decreased significantly since then.
3. In the context of psychedelic hallucinogens, identify a difference between indoleamines and phenylethylamines.
a) Indoleamines are schedule II drugs, whereas phenylethylamines are schedule III drugs.
b) Indoleamines are naturally occurring psychedelics, whereas phenylethylamines are synthetic psychedelics.
c) Indoleamines are structurally similar to serotonin, whereas phenylethylamines are structurally similar to norepinephrine and dopamine.
4. Which of the following is a difference between PCP and ketamine?
a) PCP is a psychedelic hallucinogen, whereas ketamine is a deliriant hallucinogen.
b) Unlike PCP, ketamine has anesthetic qualities and produces delusions and hallucinations.
c) PCP is currently a schedule II drug, whereas ketamine is a schedule III drug.
5. Which of the following statements is true regarding the effective doses of hallucinogenic drugs?
a) An effective dose of psilocybin is 50-100 micrograms.
b) An effective dose of mescaline is 10-20 micrograms.
c) An effective dose of LSD is 75-125 micrograms.
6. Identify a true statement about the routes of administration of various hallucinogens
a) Psilocybin mushrooms are typically smoked and cannot be ingested.
b) Snorting is the most popular route of administration for PCP.
c) MDMA is generally taken orally as a tablet or capsule.
7. Which of the following statements is true of the mechanism of action of MDMA?
a) MDMA increases activity in the amygdala.
b) MDMA blocks the release of dopamine.
c) MDMA increases the release of serotonin into the synapse.
8. Which of the following statements is true of the mechanism of action of deliriant and dissociative hallucinogens?
a) Dissociative anesthetic drugs decrease the synthesis and release of dopamine.
b) Anticholinergics such as scopolamine and atropine enable acetylcholine to bind to muscarinic receptors.
c) The dissociative anesthetic drugs ketamine and PCP bind to and block glutamatergic NMDA receptors.
9. Which of the following statements is true in the context of the results of studies focused on the therapeutic effects of psilocybin and LSD on cancer patients?
a) Cancer patients who received psilocybin showed significantly more depression and anxiety.
b) LSD had no impact on dying cancer patients’ responsiveness with family members.
c) Cancer patients who no longer responded to conventional pain treatments experienced relief with LSD.
10. Which of the following statements is true of the studies focused on the therapeutic effects of psychedelic drugs?
a) They are usually double-blind studies.
b) They are extensive with results that can be extrapolated for the general population.
c) They usually have a very small sample size.
11. Which of the following is true of the physiological effects of MDMA?
a) It can increase sensitivity to pain and boost the appetite.
b) It constricts the bronchioles and decreases sweating.
c) It can lead to muscle tension and tremor, jaw tension, and teeth grinding.
12. Identify a true statement about the physiological effects of deliriants.
a) They produce hypothermia and contracted pupils.
b) They lead to lowered heartbeat and blood pressure.
c) They produce flushed skin and constipation.
